Anti-GINS1 Polyclonal Antibody (HA800014)

Name: Anti-GINS1 Polyclonal Antibody
Brand: abinScience
SKU: HA800014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA800014

설명

Anti-GINS1 Polyclonal Antibody (HA800014) is a rabbit polyclonal antibody detecting DNA replication complex GINS protein PSF1; GINS complex subunit 1; GINS1; KIAA0186; PSF1 in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human GINS1 (Met1-Ser196).

타겟

DNA replication complex GINS protein PSF1; GINS complex subunit 1; GINS1; KIAA0186; PSF1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q14691, A4IFH4, Q9CZ15, Q7ZT47

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

DNA replication complex GINS protein PSF1 (GINS1) is a ~22 kDa protein. Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

1. Kamada, K. et al. (2007) Nature structural & molecular biology 14, 388-96. PMID: 17417653

2. Cottineau, J. et al. (2017) The Journal of clinical investigation 127, 1991-2006. PMID: 28414293

3. Rzechorzek, NJ. et al. (2020) Nucleic acids research 48, 6980-6995. PMID: 32453425

4. Jones, ML. et al. (2021) The EMBO journal 40, e108819. PMID: 34694004

5. Jenkyn-Bedford, M. et al. (2021) Nature 600, 743-747. PMID: 34700328

6. Baris, Y. et al. (2022) Nature 606, 204-210. PMID: 35585232

참고사항

For research use only

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참고 문헌

데이터시트

Anti-GINS1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-GINS1 Polyclonal Antibody (HA800014)

개요

이미지

참고 문헌

데이터시트

SDS