

| 카탈로그 번호 | HY371014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GLI1 (Phe2-Glu234). | ||||||||
| 타겟 | Oncogene GLI, GLI, Glioma-associated oncogene, GLI1, Zinc finger protein GLI1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P08151 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Zinc finger protein GLI1 is a ~117 kDa protein. Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. 1. Murone, M. et al. (2000) Nature cell biology 2, 310-2. PMID: 10806483 2. Lo, HW. et al. (2009) Cancer research 69, 6790-8. PMID: 19706761 3. Maloverjan, A. et al. (2010) Experimental cell research 316, 627-37. PMID: 19878745 4. Gilder, AS. et al. (2013) Biochemical and biophysical research communications 440, 431-6. PMID: 24076122 5. Zhang, Y. et al. (2013) Nature communications 4, 2608. PMID: 24217340 6. Cherry, AL. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 2563-79. PMID: 24311597 7. Kinzler, KW. et al. (1990) Molecular and cellular biology 10, 634-42. PMID: 2105456 8. Pavletich, NP. et al. (1993) Science (New York, N.Y.) 261, 1701-7. PMID: 8378770 | ||||||||
| 참고사항 | For research use only. |
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