Anti-Human GLP-1R Polyclonal Antibody (HW328014)

Name: Anti-Human GLP-1R Polyclonal Antibody
Brand: abinScience
SKU: HW328014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HW328014

설명

Anti-GLP1R Polyclonal Antibody (HW328014) is a rabbit polyclonal antibody detecting GLP1R in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human GLP1R (Arg24-Tyr145).

타겟

GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R

정제

Purified by antigen affinity column.

등록번호

P43220

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722

2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095

3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125

4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449

5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895

6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285

7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712

참고사항

For research use only.

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