

| 카탈로그 번호 | HF524014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GLRX3 Polyclonal Antibody (HF524014) is a rabbit polyclonal antibody detecting GLRX3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GLRX3 (Val10-Ser117). | ||||||||
| 타겟 | PKCq-interacting protein, PKC-theta-interacting protein, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, GLRX3, Thioredoxin-like protein 2, TXNL2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O76003 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Glutaredoxin-3 (GLRX3) is a ~37 kDa protein. Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. 1. Banci, L. et al. (2015) Journal of the American Chemical Society 137, 16133-43. PMID: 26613676 2. Frey, AG. et al. (2016) The Journal of biological chemistry 291, 22344-22356. PMID: 27519415 3. Haunhorst, P. et al. (2013) Molecular biology of the cell 24, 1895-903. PMID: 23615448 | ||||||||
| 참고사항 | For research use only. |
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