

| 카탈로그 번호 | HF014014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GLUD1 Polyclonal Antibody (HF014014) is a rabbit polyclonal antibody detecting GLUD1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Hylobates lar.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GLUD1 (Asp334-Thr556). | ||||||||
| 타겟 | GLUD1, GDH 1, Glutamate dehydrogenase 1, mitochondrial, GLUD | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P00367 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Glutamate dehydrogenase 1, mitochondrial (GLUD1) is a ~61 kDa protein. Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. 1. Plaitakis, A. et al. (2000) Journal of neurochemistry 75, 1862-9. PMID: 11032875 2. Smith, TJ. et al. (2001) Journal of molecular biology 307, 707-20. PMID: 11254391 3. Choi, MM. et al. (2005) FEBS letters 579, 4125-30. PMID: 16023112 4. Haigis, MC. et al. (2006) Cell 126, 941-54. PMID: 16959573 5. MacMullen, C. et al. (2001) The Journal of clinical endocrinology and metabolism 86, 1782-7. PMID: 11297618 6. Stanley, CA. et al. (1998) The New England journal of medicine 338, 1352-7. PMID: 9571255 | ||||||||
| 참고사항 | For research use only. |
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