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| 카탈로그 번호 | VK520014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-glycoprotein B/gB Polyclonal Antibody (VK520014) is a rabbit polyclonal antibody in ELISA, IHC, WB. Suitable for Human herpesvirus 2 and Human herpesvirus 1.
Highlights
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| 종 반응성 | Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2), Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant hsv1/hhv-1 glycoprotein B/gB (Asn141-Thr459). | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P06437, P08665, P10211, P06763, P08666, P06436, P24994 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Envelope glycoprotein B (gB) is a ~100 kDa protein. Envelope glycoprotein that forms spikes at the surface of virion envelope and binds to the host cell entry receptors MYH9/NMMHC-IIA and MYH10/NMMHC-IIB, promoting the virus entry into host cells. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell: following initial binding to its host cell entry receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation). | ||||||||
| 참고사항 | For research use only |
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