Anti-GNA11 Polyclonal Antibody (HB814014)

Name: Anti-GNA11 Polyclonal Antibody
Brand: abinScience
SKU: HB814014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB814014

설명

Anti-GNA11 Polyclonal Antibody (HB814014) is a rabbit polyclonal antibody detecting GNA11 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human GNA11 (Met1-Val359).

타겟

G-protein subunit alpha-11, Guanine nucleotide-binding protein G(y) subunit alpha, GNA11, G alpha-11, GA11, Guanine nucleotide-binding protein subunit alpha-11

정제

Purified by antigen affinity column.

등록번호

P29992

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Guanine nucleotide-binding protein subunit alpha-11 (GNA11) is a ~42 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.

1. Maeda, S. et al. (2019) Science (New York, N.Y.) 364, 552-557. PMID: 31073061

2. Alvarez-Curto, E. et al. (2016) The Journal of biological chemistry 291, 27147-27159. PMID: 27852822

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-GNA11 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-GNA11 Polyclonal Antibody (HB814014)

개요

이미지

참고 문헌

데이터시트

SDS

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