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| 카탈로그 번호 | HD433014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GNL2 Polyclonal Antibody (HD433014) is a rabbit polyclonal antibody detecting GNL2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GNL2 (Glu195-Arg455). | ||||||||
| 타겟 | Autoantigen NGP-1, GNL2, NGP1, Nucleolar GTP-binding protein 2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q13823 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Q13823 | ||||||||
| 배경 | Nucleolar GTP-binding protein 2 (GNL2) is a ~83 kDa protein. GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels. 1. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547 2. Datta, D. et al. (2015) The Journal of biological chemistry 290, 21536-52. PMID: 26203195 | ||||||||
| 참고사항 | For research use only |
Western blot analysis was performed using anti-GNL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate
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