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| 카탈로그 번호 | HB590014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GPR137B Polyclonal Antibody (HB590014) is a rabbit polyclonal antibody detecting Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human GPR137B (Val315-Gly399). | ||||||||
| 타겟 | Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O60478, Q8BNQ3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Integral membrane protein GPR137B is a ~45 kDa protein. Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy. 1. Gan, L. et al. (2019) Nature cell biology 21, 614-626. PMID: 31036939 | ||||||||
| 참고사항 | For research use only |
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