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Anti-GSTP1 Polyclonal Antibody (HY345014)

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개요
카탈로그 번호HY345014
설명
Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human GSTP1 (Met1-Gln210).
타겟 GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P
정제 Purified by antigen affinity column.
등록번호 P09211
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159
2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427
3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974
4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911
5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276
6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474
7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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