

| 카탈로그 번호 | HY345014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GSTP1 (Met1-Gln210). | ||||||||
| 타겟 | GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P09211 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. 1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159 2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427 3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974 4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911 5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276 6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474 7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448 | ||||||||
| 참고사항 | For research use only. |
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