Anti-GUCA1A Polyclonal Antibody (HA643014)

Name: Anti-GUCA1A Polyclonal Antibody
Brand: abinScience
SKU: HA643014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA643014

설명

Anti-GUCA1A Polyclonal Antibody (HA643014) is a rabbit polyclonal antibody detecting Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human GUCA1A (Met1-Gly201).

타겟

Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P43080, P46065, P43081

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Guanylyl cyclase-activating protein 1 (GUCA1A) is a ~22 kDa protein. Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.

1. Jiang, L. et al. (2008) Vision research 48, 2425-32. PMID: 18706439

2. Kitiratschky, VB. et al. (2009) Human mutation 30, E782-96. PMID: 19459154

3. Marino, V. et al. (2018) Human molecular genetics 27, 4204-4217. PMID: 30184081

4. Peshenko, IV. et al. (2019) The Journal of biological chemistry 294, 3476-3488. PMID: 30622141

참고사항

For research use only

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참고 문헌

데이터시트

Anti-GUCA1A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-GUCA1A Polyclonal Antibody (HA643014)

개요

이미지

참고 문헌

데이터시트

SDS

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