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| 카탈로그 번호 | VK764014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody (VK764014) is a rabbit polyclonal antibody detecting Fiber protein in ELISA, WB.
Highlights
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| 종 반응성 | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) | ||||||||
| 응용 분야 | ELISA, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant HAdV-5 Fiber protein/L5 (Gly387-Glu581). | ||||||||
| 타겟 | Fiber protein, SPIKE, Protein IV, L5 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P11818 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Fiber protein (L5) is a ~61 kDa protein. Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host coxsackievirus and adenovirus receptor CXADR located at the cell tight junctions to provide virion initial attachment to target cell. The fiber protein binds to CXADR with a higher affinity than CXADR binds to itself, thereby blocking the cell-cell adhesion function of CXADR dimers and leading to local disruption of the tight junction. Fiber protein present on neo-synthesized particles may thus disrupt the junctional integrity in order to facilitate further neighboring cells infection. Fiber proteins are shed during virus entry, when virus is still at the cell surface. | ||||||||
| 참고사항 | For research use only. |
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