

| 카탈로그 번호 | HA575014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HAND2 Polyclonal Antibody (HA575014) is a rabbit polyclonal antibody detecting HAND2 in ELISA, IHC, WB. Suitable for Mus musculus, Rattus norvegicus, Human, Xenopus laevis, and Gallus gallus.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant HAND2 (Ser2-Gln217). | ||||||||
| 타겟 | Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum heart autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, HAND2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q61039, P61295, P61296, P57101, Q90690 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Heart- and neural crest derivatives-expressed protein 2 (HAND2) is a ~23 kDa protein. Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. | ||||||||
| 참고사항 | For research use only |
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