

| 카탈로그 번호 | RD448014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HAO1 Polyclonal Antibody (RD448014) is a rabbit polyclonal antibody detecting HAO1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Rat HAO1 (Asp61-Ile370). | ||||||||
| 타겟 | 2-Hydroxyacid oxidase 1, EC:1.1.3.15, EC:1.2.3.5, GO, GOX, GOX1, Glycolate oxidase, Glyoxylate oxidase, HAO1, HAOX1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | B0BNF9 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | B0BNF9 | ||||||||
| 배경 | 2-Hydroxyacid oxidase 1 (HAO1) is a ~40 kDa protein. Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. | ||||||||
| 참고사항 | For research use only |

Western blot analysis was performed using anti-HAO1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat liver lysate


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