

| 카탈로그 번호 | HV192014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human HAS2 (Glu67-Thr172). | ||||||||
| 타겟 | HA synthase 2, Hyaluronan synthase 2, Hyaluronic acid synthase 2, HAS2, Hyaluronate synthase 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q92819 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Hyaluronan synthase 2 (HAS2) is a ~63 kDa protein. Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer (Probable). Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan. 1. Karousou, E. et al. (2010) The Journal of biological chemistry 285, 23647-54. PMID: 20507985 2. Vigetti, D. et al. (2011) The Journal of biological chemistry 286, 7917-7924. PMID: 21228273 3. Rilla, K. et al. (2013) The Journal of biological chemistry 288, 5973-83. PMID: 23303191 4. Kasai, K. et al. (2020) Biochemical and biophysical research communications 533, 732-738. PMID: 32993960 5. Watanabe, K. et al. (1996) The Journal of biological chemistry 271, 22945-8. PMID: 8798477 | ||||||||
| 참고사항 | For research use only. |
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