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| 카탈로그 번호 | VK506044 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HCV Protease NS2 Polyclonal Antibody (VK506044) is a rabbit polyclonal antibody detecting Protease NS2. Suitable for Hepatitis C virus genotype 3a.
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| 종 반응성 | Hepatitis C Virus (HCV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant HCV Protease NS2 (Leu902-Glu1026). | ||||||||
| 타겟 | Capsid protein C, Core protein precursor, EC:2.7.7.48, EC:3.4.21.98, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, Hepacivirin, Mature core protein, NS1, NS2, NS3 helicase, NS3 protease, NS3P, NS4A, NS4B, NS5A, NS5B, Non-structural protein 2, Non-structural protein 4A, Non-structural protein 4B, Non-structural protein 5A, Protease NS2, RNA-directed RNA polymerase, Serine protease/helicase NS3, Viroporin p7, Viroporin p70, gp32, gp35, gp68, gp70, p21, p23, p27, p56/58, p68, p8 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q81258 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Genome polyprotein (Protease NS2) is a ~329 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Jackel-Cram, C. et al. (2007) Journal of hepatology 46, 999-1008. PMID: 17188392 | ||||||||
| 참고사항 | For research use only |
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