

| 카탈로그 번호 | HV304014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HEPH Polyclonal Antibody (HV304014) is a rabbit polyclonal antibody detecting HEPH in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human HEPH (Ala24-Cys366). | ||||||||
| 타겟 | HEPH, KIAA0698, Hephaestin | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9BQS7 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Hephaestin is a ~130 kDa protein. Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body. 1. Vashchenko, G. et al. (2012) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 17, 1187-95. PMID: 22961397 2. Baringer, SL. et al. (2023) Journal of biomedical science 30, 36. PMID: 37277838 | ||||||||
| 참고사항 | For research use only. |
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