

| 카탈로그 번호 | HY126014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HEXA Polyclonal Antibody (HY126014) is a rabbit polyclonal antibody detecting HEXA in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human HEXA (His318-Thr529). | ||||||||
| 타겟 | Beta-hexosaminidase subunit alpha, HEXA, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P06865 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Beta-hexosaminidase subunit alpha (HEXA) is a ~60 kDa protein. Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. 1. Hepbildikler, ST. et al. (2002) The Journal of biological chemistry 277, 2562-72. PMID: 11707436 2. Novak, A. et al. (1994) Biochimica et biophysica acta 1199, 215-23. PMID: 8123671 3. Hou, Y. et al. (1996) Biochemistry 35, 3963-9. PMID: 8672428 4. Hou, Y. et al. (1998) The Journal of biological chemistry 273, 21386-92. PMID: 9694901 | ||||||||
| 참고사항 | For research use only. |
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