Anti-HEXB Polyclonal Antibody (HY435014)

Name: Anti-HEXB Polyclonal Antibody
Brand: abinScience
SKU: HY435014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HY435014

설명

Anti-HEXB Polyclonal Antibody (HY435014) is a rabbit polyclonal antibody detecting HEXB in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human HEXB (Lys315-Tyr456).

타겟

N-Acetyl-β-glucosaminidase (NAG), chitobiase, NAG, Beta-hexosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, N-acetyl-beta-glucosaminidase subunit beta, Cervical cancer proto-oncogene 7 protein, Hexosaminidase subunit B, HCC-7, HEXB

정제

Purified by antigen affinity column.

등록번호

P07686

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Beta-hexosaminidase subunit beta (HEXB/HCC7) is a ~63 kDa protein. Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida.

1. Hepbildikler, ST. et al. (2002) The Journal of biological chemistry 277, 2562-72. PMID: 11707436

2. Novak, A. et al. (1994) Biochimica et biophysica acta 1199, 215-23. PMID: 8123671

3. Hou, Y. et al. (1996) Biochemistry 35, 3963-9. PMID: 8672428

4. Hou, Y. et al. (1998) The Journal of biological chemistry 273, 21386-92. PMID: 9694901

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-HEXB Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-HEXB Polyclonal Antibody (HY435014)

개요

이미지

참고 문헌

데이터시트

SDS

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