Anti-HIC1 Polyclonal Antibody (HA798014)

Name: Anti-HIC1 Polyclonal Antibody
Brand: abinScience
SKU: HA798014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HA798014

설명

Anti-HIC1 Polyclonal Antibody (HA798014) is a rabbit polyclonal antibody detecting Hypermethylated in cancer 1 protein; Hic-1; Zinc finger and BTB domain-containing protein 29; HIC1; ZBTB29 in ELISA, IHC, WB. Suitable for Human, Mouse, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human HIC1 (Lys561-Thr733).

타겟

Hypermethylated in cancer 1 protein; Hic-1; Zinc finger and BTB domain-containing protein 29; HIC1; ZBTB29

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q14526, Q9R1Y5, Q9JLZ6, Q90W33, Q96JB3

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Hypermethylated in cancer 1 protein (HIC1) is a ~76 kDa protein. Transcriptional repressor. Recognizes and binds to the consensus sequence '5-[CG]NG[CG]GGGCA[CA]CC-3'. May act as a tumor suppressor. Involved in development of head, face, limbs and ventral body wall. Involved in down-regulation of SIRT1 and thereby is involved in regulation of p53/TP53-dependent apoptotic DNA-damage responses.

1. Deltour, S. et al. (2002) Molecular and cellular biology 22, 4890-901. PMID: 12052894

2. Pinte, S. et al. (2004) The Journal of biological chemistry 279, 38313-24. PMID: 15231840

3. Zhang, W. et al. (2010) Oncogene 29, 2467-76. PMID: 20154726

4. Chen, WY. et al. (2005) Cell 123, 437-48. PMID: 16269335

5. Van Rechem, C. et al. (2010) Molecular and cellular biology 30, 4045-59. PMID: 20547755

6. Valenta, T. et al. (2006) The EMBO journal 25, 2326-37. PMID: 16724116

7. Briggs, KJ. et al. (2008) Genes & development 22, 770-85. PMID: 18347096

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-HIC1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-HIC1 Polyclonal Antibody (HA798014)

개요

이미지

참고 문헌

데이터시트

SDS