

| 카탈로그 번호 | HY063024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HMOX1 Polyclonal Antibody (HY063024) is a rabbit polyclonal antibody detecting HMOX1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human HMOX1 (Gln11-Ser229). | ||||||||
| 타겟 | Heme oxygenase 1, HO-1, EC:1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 관찰된 분자량 | ~30 kDa | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P09601, P14901 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Heme oxygenase 1 (HMOX1) is a ~32 kDa protein. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis. 1. Lightning, LK. et al. (2001) The Journal of biological chemistry 276, 10612-9. PMID: 11121422 2. Hwang, HW. et al. (2009) The Journal of biological chemistry 284, 22672-9. PMID: 19556236 3. Wilks, A. et al. (1995) Biochemistry 34, 4421-7. PMID: 7703255 4. Gozzelino, R. et al. (2010) Annual review of pharmacology and toxicology 50, 323-54. PMID: 20055707 | ||||||||
| 참고사항 | For research use only |
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