Anti-HNRNPA2B1 Polyclonal Antibody (HB093014)

Name: Anti-HNRNPA2B1 Polyclonal Antibody
Brand: abinScience
SKU: HB093014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HB093014

설명

Anti-HNRNPA2B1 Polyclonal Antibody (HB093014) is a rabbit polyclonal antibody detecting HNRNPA2B1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human HNRNPA2B1 (Arg21-Gly103).

타겟

Heterogeneous nuclear ribonucleoproteins A2/B1, HNRPA2B1, hnRNP A2/B1, HNRNPA2B1

정제

Purified by antigen affinity column.

등록번호

P22626

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) is a ~37 kDa protein. Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs. Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm.

1. He, Y. et al. (2009) Cellular and molecular life sciences : CMLS 66, 1239-56. PMID: 19099192

2. Munro, TP. et al. (1999) The Journal of biological chemistry 274, 34389-95. PMID: 10567417

3. Alarcón, CR. et al. (2015) Cell 162, 1299-308. PMID: 26321680

4. Villarroya-Beltri, C. et al. (2013) Nature communications 4, 2980. PMID: 24356509

5. David, CJ. et al. (2010) Nature 463, 364-8. PMID: 20010808

6. Wang, L. et al. (2019) Science (New York, N.Y.) 365. PMID: 31320558

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-HNRNPA2B1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

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어세이 키트

Anti-HNRNPA2B1 Polyclonal Antibody (HB093014)

개요

이미지

참고 문헌

데이터시트

SDS