

| 카탈로그 번호 | ZA251014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Honeybee Api m 4/Melittin Polyclonal Antibody (ZA251014) is a rabbit polyclonal antibody detecting Melittin in ELISA, IHC, WB.
Highlights
|
||||||||
| 종 반응성 | Apis mellifera (Honeybee) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Honeybee Api m 4/Melittin (Gly44-Gln69). | ||||||||
| 타겟 | Melittin, MEL, MLT, Allergen Api m 3, Allergen Api m III, Api m 4, MELT | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P01501 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Melittin (Api m 4) is a ~7 kDa protein. Melittin: Main toxin of bee venom with strong antimicrobial activity and hemolytic activity. It has enhancing effects on bee venom phospholipase A2 activity. This amphipathic toxin binds to negatively charged membrane surface and forms pore by inserting into lipid bilayers inducing the leakage of ions and molecules and the enhancement of permeability that ultimately leads to cell lysis. It acts as a voltage-gated pore with higher selectivity for anions over cations. The ion conductance has been shown to be voltage-dependent. 1. Park, D. et al. (2014) Peptides 53, 185-93. PMID: 24512991 2. Tosteson, MT. et al. (1985) The Journal of membrane biology 87, 35-44. PMID: 4057243 3. Schröder, E. et al. (1971) Experientia 27, 764-5. PMID: 5139482 4. Sessa, G. et al. (1969) The Journal of biological chemistry 244, 3575-82. PMID: 5794226 5. Mollay, C. et al. (1974) FEBS letters 46, 141-4. PMID: 4371280 6. Batenburg, AM. et al. (1987) FEBS letters 223, 148-54. PMID: 3666135 7. Hider, RC. et al. (1983) Biochimica et biophysica acta 728, 206-14. PMID: 6830776 8. Tosteson, MT. et al. (1981) Biophysical journal 36, 109-16. PMID: 6269667 9. Kempf, C. et al. (1982) The Journal of biological chemistry 257, 2469-76. PMID: 7061434 | ||||||||
| 참고사항 | For research use only. |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206

中文
English
한국어
日本語
Español
Français
Русский