中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | VK472014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HPV B19 NS1/Non-structural protein 1 Polyclonal Antibody (VK472014) is a rabbit polyclonal antibody detecting Non-structural protein NS1 in ELISA, IHC, WB.
Highlights
|
||||||||
| 종 반응성 | Human parvovirus B19 | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human parvovirus B19 (HPV B19) NS1/Non-structural protein 1 (Met1-Glu671). | ||||||||
| 타겟 | NS, Non-structural protein NS1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6TV13 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Initiator protein NS1 is a ~74 kDa protein. Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter. Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR). Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters. Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins. Up-regulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition. | ||||||||
| 참고사항 | For research use only. |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
