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| 카탈로그 번호 | VK556063 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Human papillomavirus 16 (HPV16), Human papillomavirus 18 (HPV18) | ||||||
| 응용 분야 | ELISA, IP, WB, ICC, IHC | ||||||
| 숙주 종 | Mouse | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG2a, kappa | ||||||
| 클론 ID | SAA2229 | ||||||
| 발현 시스템 | Mammalian cells | ||||||
| 타겟 | E7 | ||||||
| 내독소 수준 | <10 EU/mg | ||||||
| 순도 | >95% purity as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P06788 | ||||||
| RRID | Anti-HPV18 E7/Protein E7 Antibody (SAA2229) (abinScience Cat# VK556063, RRID:AB_3729825) |
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| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||||
| 대체 이름 | Protein E7, E7 | ||||||
| 배경 | Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. 1. Lau, L. et al. (2015) Science (New York, N.Y.) 350, 568-71. PMID: 26405230 | ||||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-HPV18 E7/Protein E7 Antibody (SAA2229)
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