Anti-HPV31 E7/Protein E7 Polyclonal Antibody (VK556054)

Name: Anti-HPV31 E7/Protein E7 Polyclonal Antibody
Brand: abinScience
SKU: VK556054
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

VK556054

설명

Anti-HPV31 E7 Polyclonal Antibody (VK556054) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human papillomavirus 31 (HPV31)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant HPV31 E7 (Met1-Leu98).

타겟

Protein E7, E7

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P17387

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.

참고사항

For research use only

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