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| 카탈로그 번호 | VK556153 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Human papillomavirus 31 (HPV31) | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Mouse | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG2a, kappa | ||||||
| 클론 ID | SAA2462 | ||||||
| 발현 시스템 | Mammalian cells | ||||||
| 내독소 수준 | <10 EU/mg | ||||||
| 순도 | >95% purity as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P17387 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||||
| 대체 이름 | Protein E7, E7 | ||||||
| 배경 | Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. | ||||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-HPV31 E7/Protein E7 Antibody (SAA2462)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
