

| 카탈로그 번호 | HB704014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-HSP40/DNAJB1 Polyclonal Antibody (HB704014) is a rabbit polyclonal antibody detecting DNAJB1 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human HSP40/DNAJB1 (Met1-Ile340). | ||||||||
| 타겟 | DnaJ protein homolog 1, HSP40, DnaJ homolog subfamily B member 1, DNAJB1, DNAJ1, Heat shock 40 kDa protein 1, hDj-1, HDJ1, Human DnaJ protein 1, Heat shock protein 40, HSPF1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P25685 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | DnaJ homolog subfamily B member 1 (HSP40/DNAJB1) is a ~38 kDa protein. Interacts with HSP70 and can stimulate its ATPase activity. Acts also with TTC1 as a chaperone adapter that regulates HSP70-dependent folding process by interacting with the HSP70 amino terminal region. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). 1. Oh, WK. et al. (2003) Molecules and cells 16, 84-91. PMID: 14503850 2. Shi, Y. et al. (1998) Genes & development 12, 654-66. PMID: 9499401 3. Rauch, JN. et al. (2014) The Journal of biological chemistry 289, 1402-14. PMID: 24318877 | ||||||||
| 참고사항 | For research use only. |
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