Anti-HSP90AA1 Polyclonal Antibody (HY503014)

Name: Anti-HSP90AA1 Polyclonal Antibody
Brand: abinScience
SKU: HY503014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY503014

설명

Anti-HSP90AA1 Polyclonal Antibody (HY503014) is a rabbit polyclonal antibody detecting HSP90AA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human HSP90AA1 (Ser39-Asp193).

타겟

LPS-associated protein 2, Heat shock protein HSP 90-alpha, HSPCA, HSP90A, HSP 86, Lipopolysaccharide-associated protein 2, HSP86, HSP90AA1, Heat shock 86 kDa, Renal carcinoma antigen NY-REN-38, LAP-2, HSPC1

정제

Purified by antigen affinity column.

등록번호

P07900

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Heat shock protein HSP 90-alpha (HSP90AA1) is a ~84 kDa protein. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself.

1. Forsythe, HL. et al. (2001) The Journal of biological chemistry 276, 15571-4. PMID: 11274138

2. Young, JC. et al. (2003) Cell 112, 41-50. PMID: 12526792

3. Yang, J. et al. (2005) The EMBO journal 24, 1-10. PMID: 15577939

4. Martínez-Ruiz, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 8525-30. PMID: 15937123

5. Woodford, MR. et al. (2016) Nature communications 7, 12037. PMID: 27353360

6. Woodford, MR. et al. (2017) The EMBO journal 36, 3650-3665. PMID: 29127155

7. Pearl, LH. (2016) Biopolymers 105, 594-607. PMID: 26991466

8. Verma, S. et al. (2016) Biochimie 127, 227-40. PMID: 27295069

9. Khurana, N. et al. (2015) Frontiers in oncology 5, 100. PMID: 25973397

10. Triantafilou, K. et al. (2001) Nature immunology 2, 338-45. PMID: 11276205

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-HSP90AA1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: PC-12 cell lysate
Lane 3: Hela cell lysate
Lane 4: MCF-7 cell lysate
Lane 5: Jurkat cell lysate
Lane 6: Lncap cell lysate
Lane 7: Raji cell lysate
Lane 8: Mouse brain lysate
Lane 9: Rat brain lysate

참고 문헌

데이터시트

Anti-HSP90AA1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-HSP90AA1 Polyclonal Antibody (HY503014)

개요

이미지

참고 문헌

데이터시트

SDS