Anti-Human ACADM Polyclonal Antibody (HY429014)

Name: Anti-Human ACADM Polyclonal Antibody
Brand: abinScience
SKU: HY429014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HY429014

설명

Anti-Human ACADM Polyclonal Antibody (HY429014) is a rabbit polyclonal antibody detecting ACADM in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ACADM (Lys26-Asn421).

타겟

MCADH, MCAD, ACADM, Medium chain acyl-CoA dehydrogenase, Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

정제

Purified by antigen affinity column.

등록번호

P11310

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) is a ~46 kDa protein. Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of FAO consists in the proR-proR stereospecific alpha, beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). ETF is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase has preference for fatty acyl-CoAs with saturated 6 to 12 carbons long primary chains, making it but can also catalyze longer chains such as C14 and C16.

1. Bross, P. et al. (1990) The Journal of biological chemistry 265, 7116-9. PMID: 1970566

2. He, M. et al. (2011) Molecular genetics and metabolism 102, 418-29. PMID: 21237683

3. Kelly, DP. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 9236-40. PMID: 2251268

4. Nandy, A. et al. (1996) Biochemistry 35, 12402-11. PMID: 8823175

5. Toogood, HS. et al. (2004) The Journal of biological chemistry 279, 32904-12. PMID: 15159392

6. Małecki, J. et al. (2015) The Journal of biological chemistry 290, 423-34. PMID: 25416781

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ACADM Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ACADM Polyclonal Antibody (HY429014)

개요

이미지

참고 문헌

데이터시트

SDS

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