

| 카탈로그 번호 | HF536014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human ACSL3 Polyclonal Antibody (HF536014) is a rabbit polyclonal antibody detecting ACSL3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ACSL3 (Lys581-Lys720). | ||||||||
| 타겟 | LACS 3, LACS3, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 3, ACS3, Long-chain-fatty-acid--CoA ligase 3, FACL3, ACSL3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O95573 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Fatty acid CoA ligase Acsl3 is a ~80 kDa protein. Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. 1. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490 2. Yao, H. et al. (2008) The Journal of biological chemistry 283, 849-54. PMID: 18003621 | ||||||||
| 참고사항 | For research use only. |
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