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| 카탈로그 번호 | HB949013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, FCM, IF, IHC | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kapp | ||||
| 클론 ID | LAE102 | ||||
| 타겟 | Activin receptor type-2A, EC:2.7.11.30, Activin receptor type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P27037 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. 1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401 2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306 | ||||
| 참고사항 | For research use only |
SDS-PAGE for Anti-Human ACVR2A Antibody (LAE102)
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