Anti-Human ADI1 Polyclonal Antibody (HP903014)

Name: Anti-Human ADI1 Polyclonal Antibody
Brand: abinScience
SKU: HP903014
Price: 96 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HP903014

설명

Anti-Human ADI1 Polyclonal Antibody (HP903014) is a rabbit polyclonal antibody detecting ADI1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ADI1 (Met1-Ala179).

타겟

Sip-L, Acireductone dioxygenase (Fe(2+)-requiring), ADI1, ARD, 1, 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, MTCBP-1, Submergence-induced protein-like factor, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, Fe-ARD, MTCBP1

정제

Purified by antigen affinity column.

등록번호

Q9BV57

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Acireductone dioxygenase (ADI1) is a ~21 kDa protein. Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.

1. Hirano, W. et al. (2005) Genes to cells : devoted to molecular & cellular mechanisms 10, 565-74. PMID: 15938715

2. Uekita, T. et al. (2004) The Journal of biological chemistry 279, 12734-43. PMID: 14718544

3. Yeh, CT. et al. (2001) Journal of virology 75, 11017-24. PMID: 11602742

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ADI1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ADI1 Polyclonal Antibody (HP903014)

개요

이미지

참고 문헌

데이터시트

SDS