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Anti-Human AKAP8L Polyclonal Antibody (HA275014)

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개요
카탈로그 번호HA275014
설명
Anti-Human AKAP8L Polyclonal Antibody (HA275014) is a rabbit polyclonal antibody detecting AKAP8L in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human AKAP8L (Thr354-Gly565).
타겟 Helicase A-binding protein 95, AKAP8L, Neighbor of AKAP95, Neighbor of A-kinase-anchoring protein 95, Homologous to AKAP95 protein, A-kinase anchor protein 8-like, AKAP8-like protein, HA95, NAKAP, NAKAP95, HAP95
정제 Purified by antigen affinity column.
등록번호 Q9ULX6
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

A-kinase anchor protein 8-like (AKAP8L) is a ~71 kDa protein. Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis.

1. Westberg, C. et al. (2000) The Journal of biological chemistry 275, 21396-401. PMID: 10748171
2. Yang, JP. et al. (2001) The Journal of biological chemistry 276, 30694-700. PMID: 11402034
3. Orstavik, S. et al. (2000) Biology of the cell 92, 27-37. PMID: 10761695
4. Han, I. et al. (2002) Molecular and cellular biology 22, 2136-46. PMID: 11884601
5. Martins, SB. et al. (2000) Journal of cell science 113 Pt 21, 3703-13. PMID: 11034899
6. Martins, S. et al. (2003) The Journal of cell biology 160, 177-88. PMID: 12538639
7. Li, Y. et al. (2006) Genes & development 20, 2566-79. PMID: 16980585
8. Kvissel, AK. et al. (2007) Experimental cell research 313, 2795-809. PMID: 17594903
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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