

| 카탈로그 번호 | HW329014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human ALDH1A3 Polyclonal Antibody (HW329014) is a rabbit polyclonal antibody detecting ALDH1A3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ALDH1A3 (Lys33-Pro512). | ||||||||
| 타겟 | Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase 6, ALDH1A3, RalDH3, ALDH6, Retinaldehyde dehydrogenase 3, RALDH-3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P47895 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Retinaldehyde dehydrogenase 3 (ALDH1A3) is a ~56 kDa protein. Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region. 1. Moretti, A. et al. (2016) Scientific reports 6, 35710. PMID: 27759097 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-ALDH1A3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: A549 cell lysate
Lane 2: Mouse liver lysate
Lane 3: Mouse kidney lysate
Lane 4: Rat liver lysate
Lane 5: Rat kidney lysate


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