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| 카탈로그 번호 | HV443014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AMACR (Ala2-Lys200). | ||||||||
| 타겟 | AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UHK6 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Alpha-methylacyl-CoA racemase (AMACR) is a ~42 kDa protein. Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. 1. Ferdinandusse, S. et al. (2000) Nature genetics 24, 188-91. PMID: 10655068 2. Ferdinandusse, S. et al. (2000) Journal of lipid research 41, 1890-6. PMID: 11060359 3. Schmitz, W. et al. (1995) European journal of biochemistry 231, 815-22. PMID: 7649182 | ||||||||
| 참고사항 | For research use only. |
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