Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

Name: Anti-Human AMOTL2/LCCP Polyclonal Antibody
Brand: abinScience
SKU: HP046014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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사양:

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100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HP046014

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human AMOTL2/LCCP (Ser540-Asp653).

타겟

LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989

정제

Purified by antigen affinity column.

등록번호

Q9Y2J4

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Angiomotin-like protein 2 (AMOTL2/LCCP) is a ~85 kDa protein. Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Plays a role in coupling actin fibers to cell junctions in endothelial cells and is therefore required for correct endothelial cell morphology via facilitating transcellular transmission of mechanical force resulting in endothelial cell elongation. Required for the anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane which facilitates organization of radial actin fiber structure and cellular response to contractile forces. This contributes to maintenance of cell area, size, shape, epithelial sheet organization and trophectoderm cell properties that facilitate blastocyst zona hatching.

1. Hildebrand, S. et al. (2017) Scientific reports 7, 9540. PMID: 28842668

2. Hwang, D. et al. (2021) Life science alliance 4. PMID: 34404733

3. Huang, H. et al. (2007) Development (Cambridge, England) 134, 979-88. PMID: 17293535

4. Zhao, B. et al. (2011) Genes & development 25, 51-63. PMID: 21205866

5. Kim, M. et al. (2016) EMBO reports 17, 64-78. PMID: 26598551

6. Lucci, V. et al. (2013) Gene 529, 300-6. PMID: 23911299

7. Proszynski, TJ. et al. (2013) Journal of cell science 126, 2225-35. PMID: 23525008

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human AMOTL2/LCCP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

개요

이미지

참고 문헌

데이터시트

SDS

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