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| 카탈로그 번호 | HB174014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human APEH Polyclonal Antibody (HB174014) is a rabbit polyclonal antibody detecting APEH in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human APEH (Ile458-Ser732). | ||||||||
| 타겟 | Acylamino-acid-releasing enzyme, AARE, 3.4.19.1, Acyl-peptide hydrolase, APH, Acylaminoacyl-peptidase, Oxidized protein hydrolase, OPH, APEH, D3F15S2, D3S48E, DNF15S2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P13798 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Acylamino-acid-releasing enzyme (APEH) is a ~81 kDa protein. Aminopeptidase involved in the degradation of N(alpha)-acylated peptides. Displays exopeptidase activity toward N-formyl and N-acetyl peptides with a preference for dipeptide substrates. Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Hydrolyzes N-formylated peptides likely arising from N-terminal proteolytic cleavage of bacterial and mitochondrial proteins. 1. Fujino, T. et al. (2000) Biochimica et biophysica acta 1478, 102-12. PMID: 10719179 2. Scaloni, A. et al. (1992) The Journal of biological chemistry 267, 3811-8. PMID: 1740429 3. Jones, WM. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 2194-8. PMID: 2006156 | ||||||||
| 참고사항 | For research use only. |
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