Anti-Human AQP8 Polyclonal Antibody (HC039014)

Name: Anti-Human AQP8 Polyclonal Antibody
Brand: abinScience
SKU: HC039014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC039014

설명

Anti-Human AQP8 Polyclonal Antibody (HC039014) is a rabbit polyclonal antibody detecting Aquaporin-8; AQP-8; AQP8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human AQP8 (Glu58-Gly84&Lys129-Gly156&Ser205-Trp228).

타겟

Aquaporin-8; AQP-8; AQP8

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O94778

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Aquaporin-8 (AQP8) is a ~27 kDa protein. Channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum membrane of several tissues. The transport of the ammonia neutral form induces a parallel transport of proton, at alkaline pH when the concentration of ammonia is high. However, it is unclear whether the transport of proton takes place via the aquaporin or via an endogenous pathway. Also, may transport ammonia analogs such as formamide and methylamine, a transport favourited at basic pH due to the increase of unprotonated (neutral) form, which is expected to favor diffusion. Does not transport urea or glycerol.

1. Liu, K. et al. (2006) Biology of the cell 98, 153-61. PMID: 15948717

2. Larocca, MC. et al. (2009) American journal of physiology. Gastrointestinal and liver physiology 296, G93-100. PMID: 18948439

3. Bertolotti, M. et al. (2013) Antioxidants & redox signaling 19, 1447-51. PMID: 23541115

4. Medraño-Fernandez, I. et al. (2016) Antioxidants & redox signaling 24, 1031-44. PMID: 26972385

5. Bestetti, S. et al. (2018) Science advances 4, eaar5770. PMID: 29732408

6. Danielli, M. et al. (2019) Free radical biology & medicine 131, 370-375. PMID: 30579780

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human AQP8 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human AQP8 Polyclonal Antibody (HC039014)

개요

이미지

참고 문헌

데이터시트

SDS

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