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Anti-Human ARF6 Polyclonal Antibody (HX239014)

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개요
카탈로그 번호HX239014
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human ARF6 (Met1-Ser175).
타겟 ARF6, ADP-ribosylation factor 6
정제 Purified by antigen affinity column.
등록번호 P62330
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

ADP-ribosylation factor 6 (ARF6) is a ~20 kDa protein. GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. GTP-bound form plays an important role in the transport of multiple palmitoylated proteins form the Golgi to the plasma membrane. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension.

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2. Fang, Z. et al. (2006) Molecular & cellular proteomics : MCP 5, 1437-49. PMID: 16737952
3. Ha, VL. et al. (2008) The Journal of biological chemistry 283, 14915-26. PMID: 18400762
4. Selyunin, AS. et al. (2011) Nature 469, 107-11. PMID: 21170023
5. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017
6. D'Souza-Schorey, C. et al. (1995) Experimental cell research 221, 153-9. PMID: 7589240
7. Wang, J. et al. (2023) Journal of cell science 136. PMID: 37461827
8. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216
9. Chau, DD. et al. (2022) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36, e22594. PMID: 36250347
10. Chen, KJ. et al. (2022) Journal of cell science 135. PMID: 36017701
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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