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| 카탈로그 번호 | HW643014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ARL2 (Met1-Asp184). | ||||||||
| 타겟 | ARL2, ADP-ribosylation factor-like protein 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P36404 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | ADP-ribosylation factor-like protein 2 (ARL2) is a ~20 kDa protein. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. 1. Bhamidipati, A. et al. (2000) The Journal of cell biology 149, 1087-96. PMID: 10831612 2. Zhou, C. et al. (2006) Molecular biology of the cell 17, 2476-87. PMID: 16525022 3. Muromoto, R. et al. (2008) International immunology 20, 395-403. PMID: 18234692 4. Veltel, S. et al. (2008) FEBS letters 582, 2501-7. PMID: 18588884 5. Tian, G. et al. (2010) Cytoskeleton (Hoboken, N.J.) 67, 706-14. PMID: 20740604 6. Cai, XB. et al. (2019) Clinical genetics 96, 61-71. PMID: 30945270 | ||||||||
| 참고사항 | For research use only. |
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