Anti-Human ASIC2 Polyclonal Antibody (HS947014)

Name: Anti-Human ASIC2 Polyclonal Antibody
Brand: abinScience
SKU: HS947014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HS947014

설명

Anti-Human ASIC2 Polyclonal Antibody (HS947014) is a rabbit polyclonal antibody detecting ASIC2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ASIC2 (Gln71-Lys421).

타겟

BNaC1, ACCN, ACCN1, Mammalian degenerin homolog, Acid-sensing ion channel 2, BNAC1, MDEG, Amiloride-sensitive brain sodium channel, Amiloride-sensitive cation channel 1, neuronal, ASIC2, Brain sodium channel 1, Amiloride-sensitive cation channel neuronal 1, BNC1

정제

Purified by antigen affinity column.

등록번호

Q16515

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Acid-sensing ion channel 2 (ASIC2) is a ~57 kDa protein. Forms pH-gated trimeric sodium channels that act as postsynaptic excitatory sensors in the nervous system. Upon extracellular acidification, these channels generate rapid, transient inward currents that fully desensitize. Highly selective for sodium, they are permeable to other cations. By forming heterotrimeric channels with ASIC1, could contribute to synaptic plasticity, learning, and memory. Additionally, as acid sensors at nerve terminals, plays a role in mechanosensation and phototransduction.

1. Babinski, K. et al. (2000) The Journal of biological chemistry 275, 28519-25. PMID: 10842183

2. Diochot, S. et al. (2012) Nature 490, 552-5. PMID: 23034652

3. Price, MP. et al. (1996) The Journal of biological chemistry 271, 7879-82. PMID: 8626462

4. Waldmann, R. et al. (1996) The Journal of biological chemistry 271, 10433-6. PMID: 8631835

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human ASIC2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ASIC2 Polyclonal Antibody (HS947014)

개요

이미지

참고 문헌

데이터시트

SDS