Anti-Human ATG14 Polyclonal Antibody (HP189014)

Name: Anti-Human ATG14 Polyclonal Antibody
Brand: abinScience
SKU: HP189014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HP189014

설명

Anti-Human ATG14 Polyclonal Antibody (HP189014) is a rabbit polyclonal antibody detecting ATG14 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ATG14 (Glu209-Glu415).

타겟

ATG14L, ATG14, Barkor, Atg14L, Beclin 1-associated autophagy-related key regulator, Autophagy-related protein 14-like protein, KIAA0831

정제

Purified by antigen affinity column.

등록번호

Q6ZNE5

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Beclin 1-associated autophagy-related key regulator (ATG14) is a ~55 kDa protein. Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.

1. Itakura, E. et al. (2008) Molecular biology of the cell 19, 5360-72. PMID: 18843052

2. Sun, Q. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 19211-6. PMID: 19050071

3. Matsunaga, K. et al. (2009) Nature cell biology 11, 385-96. PMID: 19270696

4. Matsunaga, K. et al. (2010) The Journal of cell biology 190, 511-21. PMID: 20713597

5. Fogel, AI. et al. (2013) Molecular and cellular biology 33, 3675-88. PMID: 23878393

6. Diao, J. et al. (2015) Nature 520, 563-6. PMID: 25686604

7. Shi, X. et al. (2023) Cell reports 42, 113045. PMID: 37632749

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ATG14 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

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어세이 키트

Anti-Human ATG14 Polyclonal Antibody (HP189014)

개요

이미지

참고 문헌

데이터시트

SDS