Anti-Human ATG7 Polyclonal Antibody (HF840014)

Name: Anti-Human ATG7 Polyclonal Antibody
Brand: abinScience
SKU: HF840014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF840014

설명

Anti-Human ATG7 Polyclonal Antibody (HF840014) is a rabbit polyclonal antibody detecting ATG7 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ATG7 (Ser19-Glu321).

타겟

hAGP7, ATG7, Ubiquitin-activating enzyme E1-like protein, APG7L, Ubiquitin-like modifier-activating enzyme ATG7, Autophagy-related protein 7, ATG12-activating enzyme E1 ATG7, APG7-like

정제

Purified by antigen affinity column.

등록번호

O95352

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ubiquitin-like modifier-activating enzyme ATG7 is a ~77 kDa protein. E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Facilitates LC3-I lipidation with phosphatidylethanolamine to form LC3-II which is found on autophagosomal membranes.

1. Collier, JJ. et al. (2021) The New England journal of medicine 384, 2406-2417. PMID: 34161705

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human ATG7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ATG7 Polyclonal Antibody (HF840014)

개요

이미지

참고 문헌

데이터시트

SDS