Anti-Human ATL2 Polyclonal Antibody (HD526014)

Name: Anti-Human ATL2 Polyclonal Antibody
Brand: abinScience
SKU: HD526014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD526014

설명

Anti-Human ATL2 Polyclonal Antibody (HD526014) is a rabbit polyclonal antibody detecting ATL2. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ATL2 (Val61-Gly365).

타겟

ADP-ribosylation factor-like protein 6-interacting protein 2, ARL6IP2, ATL-2, ATL2, Atlastin-2, EC:3.6.5.-

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q8NHH9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Atlastin-2 (ATL2) is a ~66 kDa protein. Atlastin-2 (ATL2) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-2 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi).

1. Rismanchi, N. et al. (2008) Human molecular genetics 17, 1591-604. PMID: 18270207

2. Hu, J. et al. (2009) Cell 138, 549-61. PMID: 19665976

3. Morin-Leisk, J. et al. (2011) The Journal of cell biology 195, 605-15. PMID: 22065636

4. Wang, S. et al. (2016) eLife 5. PMID: 27619977

5. Crosby, D. et al. (2022) The Journal of cell biology 221. PMID: 34817557

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human ATL2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ATL2 Polyclonal Antibody (HD526014)

개요

이미지

참고 문헌

데이터시트

SDS