Anti-Human ATP10A Polyclonal Antibody (HT395014)

Name: Anti-Human ATP10A Polyclonal Antibody
Brand: abinScience
SKU: HT395014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HT395014

설명

Anti-Human ATP10A Polyclonal Antibody (HT395014) is a rabbit polyclonal antibody detecting ATP10A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ATP10A (Glu688-Arg866).

타겟

Phospholipid-transporting ATPase VA, 7.6.2.1, ATPase class V type 10A, Aminophospholipid translocase VA, P4-ATPase flippase complex alpha subunit ATP10A, ATP10A, ATP10C, ATPVA, ATPVC, KIAA0566

정제

Purified by antigen affinity column.

등록번호

O60312

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Phospholipid-transporting ATPase VA (ATP10A) is a ~167 kDa protein. Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. Initiates inward plasma membrane bending and recruitment of Bin/amphiphysin/Rvs (BAR) domain-containing proteins involved in membrane tubulation and cell trafficking. Facilitates ITGB1/beta1 integrin endocytosis, delaying cell adhesion and cell spreading on extracellular matrix. Has low flippase activity toward glucosylceramide (GlcCer).

1. Naito, T. et al. (2015) The Journal of biological chemistry 290, 15004-17. PMID: 25947375

2. Takada, N. et al. (2018) The EMBO journal 37. PMID: 29599178

3. Roland, BP. et al. (2019) The Journal of biological chemistry 294, 1794-1806. PMID: 30530492

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ATP10A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ATP10A Polyclonal Antibody (HT395014)

개요

이미지

참고 문헌

데이터시트

SDS