Anti-Human ATP13A1 Polyclonal Antibody (HA160014)

Name: Anti-Human ATP13A1 Polyclonal Antibody
Brand: abinScience
SKU: HA160014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HA160014

설명

Anti-Human ATP13A1 Polyclonal Antibody (HA160014) is a rabbit polyclonal antibody detecting ATP13A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ATP13A1 (Ser542-Ser722).

타겟

Endoplasmic reticulum P5A-ATPase, KIAA1825, ATP13A1, Endoplasmic reticulum transmembrane helix translocase, ATP13A

정제

Purified by antigen affinity column.

등록번호

Q9HD20

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Endoplasmic reticulum transmembrane helix translocase (ATP13A1) is a ~132 kDa protein. Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.

1. McKenna, MJ. et al. (2020) Science (New York, N.Y.) 369. PMID: 32973005

2. Guna, A. et al. (2022) Science (New York, N.Y.) 378, 317-322. PMID: 36264797

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-ATP13A1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Mouse brain lysate

참고 문헌

데이터시트

Anti-Human ATP13A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ATP13A1 Polyclonal Antibody (HA160014)

개요

이미지

참고 문헌

데이터시트

SDS