

| 카탈로그 번호 | HF746014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human B3GAT3 Polyclonal Antibody (HF746014) is a rabbit polyclonal antibody detecting B3GAT3 in ELISA, IHC, WB. Suitable for Cricetulus griseus, Mus musculus, and Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human B3GAT3 (Leu74-Val335). | ||||||||
| 타겟 | B3GAT3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O94766 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, 2.4.1.135, Beta-1, 3-glucuronyltransferase 3, Glucuronosyltransferase I, GlcAT-I, UDP-GlcUA:Gal beta-1, 3-Gal-R glucuronyltransferase, GlcUAT-I, B3GAT3 | ||||||||
| 배경 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3) is a ~37 kDa protein. Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. 1. Budde, BS. et al. (2015) Human genetics 134, 691-704. PMID: 25893793 2. Koike, T. et al. (2014) The Journal of biological chemistry 289, 6695-6708. PMID: 24425863 | ||||||||
| 참고사항 | For research use only. |
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