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| 카탈로그 번호 | HA552014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human BAAT Polyclonal Antibody (HA552014) is a rabbit polyclonal antibody detecting BAAT in WB, IHC, ELISA. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | WB, IHC, ELISA | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human BAAT (Met1-Leu418). | ||||||||
| 타겟 | BAAT | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >90% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q14032 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Bile acid-CoA:amino acid N-acyltransferase, BACAT, BAT, EC:2.3.1.65, Bile acid-CoA thioesterase, Choloyl-CoA hydrolase, EC:3.1.2.27, Glycine N-choloyltransferase, Long-chain fatty-acyl-CoA hydrolase, EC:3.1.2.2, BAAT | ||||||||
| 배경 | Bile acid-CoA:amino acid N-acyltransferase (BAAT) is a ~46 kDa protein. Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. 1. Sfakianos, MK. et al. (2002) The Journal of biological chemistry 277, 47270-5. PMID: 12239217 2. O'Byrne, J. et al. (2003) The Journal of biological chemistry 278, 34237-44. PMID: 12810727 3. Johnson, MR. et al. (1991) The Journal of biological chemistry 266, 10227-33. PMID: 2037576 4. Falany, CN. et al. (1994) The Journal of biological chemistry 269, 19375-9. PMID: 8034703 | ||||||||
| 참고사항 | For research use only. |
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