Anti-Human BAZ2A Polyclonal Antibody (HD649014)

Name: Anti-Human BAZ2A Polyclonal Antibody
Brand: abinScience
SKU: HD649014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD649014

설명

Anti-Human BAZ2A Polyclonal Antibody (HD649014) is a rabbit polyclonal antibody detecting BAZ2A. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human BAZ2A (Ala535-Gly653).

타겟

BAZ2A, Bromodomain adjacent to zinc finger domain protein 2A, KIAA0314, TIP5, TTF-I-interacting protein 5, Tip5, Transcription termination factor I-interacting protein 5, hWALp3

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9UIF9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Bromodomain adjacent to zinc finger domain protein 2A (BAZ2A) is a ~211 kDa protein. Regulatory subunit of the ATP-dependent NoRC-1 and NoRC-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. Directly stimulates the ATPase activity of SMARCA5 in the NoRC-5 ISWI chromatin remodeling complex. The NoRC-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NoRC-5 ISWI chromatin remodeling complex. Within the NoRC-5 ISWI chromatin remodeling complex, mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.

1. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human BAZ2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human BAZ2A Polyclonal Antibody (HD649014)

개요

이미지

참고 문헌

데이터시트

SDS